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Svante Twetman

PhD, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen

Presentation title: The burden of oral diseases and the importance of maintaining a balanced oral microbiome

Dr Twetman is a specialised paediatric dentist and professor of Cariology and the Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. He graduated from the dental school in 1974 and holds a PhD and Ondont. Dr. degree from Karolinska Institutet, Stockholm, Sweden.

Dr Twetman’s main research focus is within fluoride and microbial aspects on oral ecology and caries prevention in childhood with a focus on clinical trials. Dr Twetman has also authored over 200 peer-reviewed papers and was awarded the IADR Distinguished Scientist Award in 2010 and the EW Borrow Memorial Award in 2011.


Although largely preventable, oral diseases remain the most common global health burden, affecting over 40% of all people worldwide. Caries and periodontitis are non-communicable diseases sharing risk factors with other lifestyle-related general diseases. Untreated and in its severe forms, they have significant social and economic consequences for communities, families and the individual quality of life. The evolving understanding on the role of the oral microbiome in health and disease has paved the way for probiotics to combat local dysbiotic environments with overabundance of saccharolytic or proteolytic bacteria in the oral ecosystem. The composition of the oral microbiome changes across the lifespan but the first 100 days of life may offer a unique window of opportunity for modulating the structure and function of the oral microbiota to promote a healthy growth and development.