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Dietary nutrients not only fuel human cells but also serve as nutrients for the microbes residing in the human intestine. Therefore, diet is vital in shaping the gut microbiota composition, functionality and activity throughout life.
The region is home to several excellent research environments and companies with a strong focus on elucidating the interplay between diet, the microbiota and health. Such insights have the potential to enable the development of personalized nutrition strategies and functional foods such as prebiotics targeting the gut microbiome in different age groups and health conditions.
Highlights from the region
Glycom, is a spin-out company of the Technical University of Denmark bought by DSM for 5.7 billion DKK in early 2020. Glycom is a recent example of a Danish company that, together with academic research groups, managed to develop and produce an ingredient for infant formula. The formula builds on insights from the interplay between breast milk and the infant gut microbiome.
Download and explore the list of research environments involved in this area:
To explore the list of companies involved in this area, try our database here
Examples of publications led by researchers affiliated to the region
Meslier, Laiola, Roager et al. (2020). Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake. Gut
Ericson et al. (2019) A Health-Conscious Food Pattern Is Associated with Prediabetes and Gut Microbiota in the Malmö Offspring Study. Journal of Nutrition
Roager, Vogt et al. (2019) A wholegrain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: A randomised cross-over trial. Gut
Ghaffarzadegan et al. (2019) Postprandial Responses of Serum Bile Acids in Healthy Humans after Ingestion of Turmeric before Medium/High‐Fat Breakfasts. Molecular Nutrition & Food Research
Leth et al. (2018) Differential Bacterial Capture and Transport Preferences Facilitate Co-Growth on Dietary Xylan in the Human Gut. Nature Microbiology
Hansen, Roager, Søndertoft, Gøbel et al. (2018). A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults. Nature Communications
Examples of projects within the segment
3G Center (Gut, Grains and Greens) - Center for Gut Microbiota, Metabolic disorders, and Grain/Fibre-based Diets